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October 2010

TrichoScience Innovations has developed and patented a non-surgical hair cell restoration procedure


The treatment has the potential to become a safe and effective non-surgical treatment for pattern baldness and other forms of hair loss in both men and women

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Oct 2010

Newcastle Resources Ltd. is pleased to announce that it has entered into a share exchange agreement (the "TrichoScience Agreement"), dated October 29, 2010, with TrichoScience Innovations Inc. ("TrichoScience") and certain accepting shareholders of TrichoScience (the "Accepting Shareholders") which represent a minimum of 55% of the issued and outstanding shares of TrichoScience.

The Company concurrently entered into a share exchange agreement (the "583885 Agreement"), dated October 29, 2010, with 583885 B.C. Ltd. ("583885") and the shareholders of 583885 (the "583885 Shareholders") including its principal shareholder David Hall.

TrichoScience Innovations Inc. is a life sciences company that has developed RepliCel(TM), a natural hair cell replication technology that has the potential to become the world's first non-surgical, permanent solution for androgenetic alopecia and general hair loss in both men and women. Patents for the TrichoScience technology have now been issued by the European Union and Australia and are pending in other major international jurisdictions.

The RepliCel(TM) procedure has been developed over the past nine years by the company's recognized research scientists and medical experts - specialists in the fields of hair growth, hair biology and dermatology.

RepliCel(TM) is based on autologous cell implantation technology that replicates a patient's hair cells from their own healthy hair follicles and, when reintroduced into areas of hair loss, initiates natural hair regeneration.

583885 is a private consulting company controlled and managed by David Hall which is currently providing management consulting services to TrichoScience.

About Trichoscience

New Hair from Replicated Cells

TrichoScience Innovations has developed and patented a non-surgical hair cell restoration procedure based on the clinical replication of hair root cells and their re-introduction into areas of hair loss. The treatment has the potential to become a safe and effective non-surgical treatment for pattern baldness and other forms of hair loss in both men and women.

Developed by Renowned Specialists

The TrichoScience procedure was developed over the past ten years by recognized research scientists and medical experts specializing in the fields of hair growth, hair biology and dermatology. Visit our Medical Team page for more information.

Clinical Trials

The TrichoScience proprietary hair cell replication procedure has shown promising results in laboratory test models. Based on these results, the TrichoScience team has started development of a human clinical trial program. The team is on track to start in Europe on their first-in-human research protocol in the second half of 2010.

Note: TrichoScience is not recruiting subjects for the trial program and cannot accept volunteers by email or through other communications. Study recruitment is conducted by an independent party and their contact details cannot be provided by TrichoScience.

hair stem cells
Procedure

Although the TrichoScience procedure employs leading edge science in cell replication, the mechanics of the procedure are relatively simple.

About 10-20 healthy hair follicles are extracted from the back of a patient’s scalp. Certain cells from these follicles are then isolated and replicated in a laboratory through the TrichoScience proprietary hair cell replication procedure.

The replicated cells are then injected back into the patient’s bald scalp. Laboratory models have shown that when these types of cells are injected back into the skin; they rejuvenate damaged hair follicles and induce the formation of new hair follicles.

While long-term research on this technology is still under development, it is expected that these injections will have a long- lasting effect on hair growth.


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