Nisim
A unique deep cleansing
shampoo
guaranteed to reduce hair loss.
Price approx $12/£8
Ingredients |
Guarantee
| Clinical Study
This unique deep cleansing shampoo has been specially
formulated to maximize a clean and nutrient rich
environment for healthy hair growth. The shampoo
effectively removes build up of sweat, oils, and dirt etc
as well as neutralizing the DHT on the surface of the
scalp. DHT is the most common cause of hair loss.
The shampoo has been developed and tested to work in
harmony with the Nisim NewHair Biofactors Hair
Stimulating Extract. Use this shampoo as your first step
in the advanced NewHair Biofactors system, available for
both oily to normal hair and dry to normal hair.
Nisim Shampoos are GUARANTEED to reduce excessive
hair loss for men or women within one week. Nisim
Shampoos can be used as a stand alone product, no
unnecessary expense buying 3-4 products. Proper use of
shampoo alone can help you maintain your existing hair.
It is very important that you wash your hair daily, and
that you wash rinse and repeat.
Ingredients
Herbal Extract
The most important ingredients in our product. The
herbal's all have very important functions. The odd
numbered carbon fatty acids help nourish the hair
follicle and promote follicle stimulation. The saw
palmetto extract contains cyclic ringed carbons that
prevent damage to the scalp that can lead to hair loss.
The scalp and skin can be compared to the bricks and
mortar of a wall. The bricks represent the cells and the
mortar is the intracellular substance between your
cells. Nisim has herbal's that have been selectively
analyzed to be small enough to penetrate the "mortar"
portion of your cells and then into the hair. Our unique
microencapsulation and microemullsion delivery system
allows for maximum results in minimal time.
Sulfur containing Amino Acids
Amino acids are the building blocks for proteins. Our
hair is composed of proteins, the most abundant amino
acids in hair are the sulfur containing amino acids
cystine, cysteine and methionine. By incorporating these
"building blocks" we supply the hair and underlying
matrix with the essential building blocks necessary for
healthy hair growth and renewal.
Panthenol
Provitamin B5 nourishes and encapsulates the hair
providing strength and support.
Inositol
A cyclic sugar alcohol that supplies energy to the
hair and the underlying matrix.
Biotin
A member of the B vitamin family necessary and
essential for optimizing healthy hair growth.
Natural Vasodilators
Contained in our herbal's are natural occurring
Nitroxide compounds that can increase the peripheral
circulation of the scalp allowing for all the essential
amino acids and other nutrients to be utilized by the
hair and scalp.
Extract - Other Ingredients
Distilled water, alcohol, thistle extract. saw
palmetto extract, rosemary extract, chamomile extract,
horsetail extract, cystine, cysteine, methionine.
Gel Extract - Other Ingredients
Distilled water, alcohol, thistle extract. saw
palmetto extract, rosemary extract, chamomile extract,
horsetail extract, cystine, cysteine, methionine,
Hyaluronic acid, beta glucan
Shampoos - Ingredients
Distilled water, sodium laureth sulfate, sodium
laurel sulfate, cocamidopropyl betaine, sodium chloride,
cocamide DEA, herbal extract, inositol, panthenol,
cystine, cysteine, methionine, biotin, citric acid,
fragrance, methylchlorisothiazolinone,
methylisothiazolinone, D & C Red # 33 and FD & C Yellow
#5
Finishing Rinse Conditioner -
Ingredients
Distilled water, cetyl alcohol, cetearyl alcohol,
PEG-40, hydrogenated castor oil, polyquaternium-7,
propylene glycol, vitamin E (tocopherol), inositol,
panthenol, horsetail extract, ginseng extract, chamomile
extract, rosemary extract, stearalkonium chloride,
cystine, cysteine, methionine, fragrance, propylparaben,
methylparaben, F D & C Yellow #5, D & C Red #33
Oil Free Conditioner - Ingredients
Distilled water, myristamine oxide, cetrimonium
chloride, propylene glycol, sulfur containing amino
acids, inositol, pantothenol, polyquaternium-10,
DEA-oleth-2-phosphate, biotin, citric acid, sodium
chloride, phenoxyethanol, methylparaben, propylparaben,
fragrance
Spray Conditioner - Ingredients
Distilled water, PEG-40, hydrogenated castor oil,
PEG-15, tallow polyamine, pantothenol, inositol, sulfur
containing amino acids, ester of fatty acids,
polyglycolic esters, cetyl alcohol, methylparaben,
propylparaben, fragrance, and color
A Clinical Study on New Hair Biofactors
Summary
One-hundred and forty-eight participants with varying
degrees of male pattern baldness (androgenic alopecia)
participated in an open-ended study using an all natural
compound solution to determine the effects of hair
regrowth.
The participants were photographed and initial hair
counts were done in a 2.5 cm diameter area of their
balding scalp. After five months of treatment, the
participants were re-photographed and hair counts were
done on the same 2.5 cm diameter area of the scalp. The
results indicate that 85.7% of the men in the study had
an increase in their terminal hairs of 30% or greater.
When evaluating the percent increase more closely, we
find that we can break the date down into three separate
groups:
1. Significant regrowth
2. Moderate regrowth
3. No change
Showing significant regrowth was 40.8% of the study
group and had an increase of 100% or greater (doubling,
tripling, or more) of terminal hairs counted on their
five month post-treatment photo as compared to their
initial pre-treatment photo. Of this group, the highest
increase of hairs was 472%, and the lowest increase was
102% with the mean at 193.7% increase of hairs.
The group of men showing moderate regrowth, which we
classed as 30%-100% increase in terminal hair regrowth,
was 44.9% of the study group. The mean increase of that
group was a 61.5% increase of hair regrowth.
The remainder of the group, classed as no change, was
14.3% of the study group, with an average of 6.7%
increase in regrowth.
Participants were told to use at least one bottle per
month (five bottles in five months) but were allowed to
use more if desired. We did not see any significant
advantage to using more than one bottle per month. Our
conclusion is that the stimulatory effect of the
compound is achieved at the use rate of one bottle per
month.
The age range of the participants in the ability to
regrow hair was not a factor. The range of the
participants in this study was 24-68 years old, with the
average age being 38.7 years.
In summary, this study concludes that the natural
herbal extract solution has a stimulatory effect on hair
growth for at least 8 out of 10 men with androgenic
alopecia (balding). The earlier stages of balding appear
to respond to a higher degree, but significant
improvement was seen in participants at all stages of
baldness. There appears to be an optimum rate of use of
the product, and age does not seem to be a factor in
response.
Introduction
Hair performs no vital function relative to the
medical well being of humans. Yet the psycho-social
implications can never be underestimated. Scalp hair can
be the crowning glory for the femininity of women and a
potent symbol of masculinity and security in men.
Reversal of male pattern baldness in men has for
centuries eluded science and medicine. Minoxidil
(commonly known as Rogaine) and Diazoxide have shown in
past studies to reverse balding in men, although in only
small percentages of the patients studied.
This study demonstrated the safety and efficacy of a
natural compound solution to stimulate hair growth. The
solution is coupled with a treatment regimen which
includes scalp cleansing and proper scalp massaging.
Patients and Methods
One hundred and sixty four males with male pattern
baldness from the greater Toronto area were studied at
the hair clinic. After informed consent and observing
past medical histories and years of balding, the men
were selected. Patients that were using any form
corticosteroids, cytotoxic agents, or any other form of
hair regrowth agent like minoxidil were excluded from
the study.
It was decided to run an open-ended study. All men
were instructed and shown very carefully how to use the
specially formulated scalp cleanser and all natural
compound solution. Once this was handled, all the men
were photographed with a high resolution Minolta
"instant pro" camera. The room was brightly illuminated
for close examination of the scalp and individual hairs.
The camera was positioned exactly 25 cm from the balding
or thinning areas with frontal, top, and rear pictures
taken as needed. The participants were asked to wait for
the picture to develop and sign their respective photos.
* Administration and Dosage
The all natural compound solution was supplied at no
charge to the participants. Each person received 250 ml
of the alcohol based all natural compound solution along
with 250 ml of a specially formulated deep scalp
cleanser. They were all individually and carefully
instructed on the proper usage of both the scalp
cleanser and the all natural compound solution.
* Evaluation and Assessment
Grading
The photos taken prior to the treatment were closely
evaluated. Before the treatment was initiated, a 2.5 cm
circle in diameter was drawn in the balding area, always
very near the border of the area demonstrating the most
significant hair loss. Initial hair counts were done
using a 4X magnifying lens mounted on a circular
fluorescent lamp. Independent counts were made by two of
us (MS and AJF), times 2, and the average of the two
counters was used for statistical purposes. The hairs in
the 2.5 cm area were counted, including hairs on the
circular boundary. The final counts on the participants
were done after five (5) months on the treatment
program. The same criteria from the initial photograph
was used to determine the exact location of the 2.5 cm
area on the scalp and the same procedure was used to
count hair roots within and on the boundary of the
inscribed circular area.
At the conclusion of the five (5) month treatment
program, the photos were graded under the following
categories: A zero (0) grading was given to the photos
that revealed no change from their initial pre-treatment
photo. A grading of one (1) was given to the
participants with moderate regrowth of hair from their
respective original photos. And a grading of two (2) was
assigned to the men with a significant regrowth of hair
from their original photos.
Results
Of the one-hundred and sixty-four participants
starting the study, eleven were eliminated because of
their repeated absence from photo sessions and failure
to use the product. Four were eliminated due to their
irregular use of both the scalp cleanser and the all
natural compound solution, and one person was
discontinued because he relocated to another country.
The remainder of the 148 participants applied the all
natural compound solution at least twice daily for the
five months as required for this study.
The regrowth of hair was first noticed on some
participants as early as two months into the treatment.
By the third month, a substantial number of men
demonstrated moderate regrowth; both fine vellus hairs
(peach fuzz) and darker pigmented intermediate and
terminal hairs were observed. It is noteworthy to
mention that the fine vellus hairs, although visible to
the naked eye, were not detectable by the photos. Thus
all of our quantitative and qualitative assessments were
made from any intermediate and/or terminal hairs.
* Criteria for Analysis of Response to All Natural
Compound Solution
The following parameters were used to classify the
magnitude of hair regrowth: Subjects with less than a
30% increase in intermediate and/or terminal hairs were
counted as no change. The moderate improvement group we
determined were the men that showed an increase of final
hair counts of greater than 30% and up to a 100%
increases of terminal hairs, in their five month photos
as compared to their original photos. The last group we
identified was the significant increase group. This
group showed the best improvement of all the men in the
study, and we included those with hair count increases
of 100% or greater.
* Response of the All Natural Compound Solution on
Baldness
Although the qualitative and quantitative assessments
were done independently, there was a strong correlation
between the two groups. Overall, 88% of the qualitative
group showed some degree of improvement. Of the group
studied quantitatively, 85.7% showed a degree of
regrowth (within 95% confidence limits). With the
qualitative group, 6 of 50 men were categorized as
having no change (category 0), representing 12% of the
total. In the quantitative group (98 participants), 14
men, or 14.3% did not show any increase in hair counts.
The average hair count increase for this group was 6.7%.
So most subjects in this group did regrow some hair, but
not a noticeable amount.
The moderately improved qualitative group (category 1)
consisted of 16 participants, or 32%. In the
quantitatively studied group, 44 of 98 men fell into the
range of +30% to +100%. This represents 44.9% of the
men. The range of increase was 32% to 98%, with the mean
at 61.5% The participants showing significant regrowth
in the qualitative group (category 2) were 28 of 50, or
56%. In the quantitatively studied group, the number of
men with significant regrowth (greater than 100%) was 40
of 98, or 40.8%. These men had hair count increases of
100% or more. The range of hair count increases was 102%
to 472%, with a mean increase of 194%. The photograph of
these men and women showed significant cosmetic changes
which correlates very well with our quantitative
findings.
* Pattern of Hair Regrowth
From the photos taken monthly during the course of the
study, a pattern of regrowth was observed in those
participants who demonstrated a significant increase in
hair counts over the five months. The first countable
hairs were seen after 10-12 weeks of treatment and were
first detected on the crown or vertex of the head.
Following further treatment, hair was then observed
regrowing in the margin of fringe of the thinning or
balding areas of the scalp. Hair regrowth in the fronto-temporal
region of the scalp was noted after 16-20 weeks of
treatment, and this region appeared to be the most
resistant to regrowth to date.
* Correlation of Response with
Age
The average age of the 176 participants was 38.7
years. The mean ages for their respective groups were as
follows: The no change group was 41.8 years. The
moderate group was 36.7 years. And the significant group
was 38.5 years. The youngest participant in the study
was 24 years old, and the oldest participant was 68.
There was no correlation between age and response to the
treatment.
Discussion
This open-ended study has demonstrated the hair
regrowth response of 148 men who have been treated with
an all natural compound solution applied topically to
balding or thinning regions of the scalp. The treatment
program included regular scalp cleansing with a natural
extract scalp cleanser and application of at least 5-10
ml of the all natural compound solution at least twice
daily. The data showed that hair counts increased
significantly for approximately 85% of the participants
in the five month period.
The study methodology implies that the results
obtained relate not only to the all natural compound
solution used in the treatment, but also the overall
treatment regimen. From previous minoxidil (Rogaine)
papers, it was determined by them that a reasonable
expectation for a "placebo-type" effect was a 10-15%
increase in hair counts. Thus, by setting the cut-off in
this study for moderate regrowth at a 30% increase, any
increase due to a "placebo-type" effect is discounted.
An attempt was made to correlate the response (either
no change, moderate change, or significant change) with
a number of factors. None of the factors studied gave a
strong correlation, although there were some trends
noted. The number of years of balding or thinning hair
did not appear to have any correlation with the final
results. However, it should be noted that the number of
years thinning was a number given by the participants,
and could not be verified accurately. Thus it is a
subject of assessment and may not be very reliable. To
help balance this uncertainty, the results were grouped.
Regardless of the groupings used, there was no grouping
which demonstrated a significant correlation with
results.
In terms of hair regrowth, this all natural compound
solution appears to be more effective than minoxidil
(Rogaine) and has no known side effects. A study by
Alanis showed that a 2% minoxidil preparation applied
topically increased hair counts by about 24% after 20
weeks. This study showed an increase of 89% in the same
time period. Because of the differences in locating the
measured regions of the scalp, these results are not
directly comparable, but in a population study, Alanis's
results showed that 34-46 out of 83 participants (48%)
had no growth after 24 weeks, whereas our results show
only 14 out of 98 (14%) had no growth after 20 weeks.
Thus, our conclusion is that this product does stimulate
regrowth of hair in cases of androgenic alopecia
(balding), and that over 85% of men will respond
favorably to the treatment.
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